O-Desmethylangolensin

Modify Date: 2024-01-06 14:06:18

O-Desmethylangolensin Structure
O-Desmethylangolensin structure
Common Name O-Desmethylangolensin
CAS Number 21255-69-6 Molecular Weight 258.26900
Density 1.329g/cm3 Boiling Point 483.3ºC at 760mmHg
Molecular Formula C15H14O4 Melting Point N/A
MSDS Chinese USA Flash Point 260.2ºC

 Use of O-Desmethylangolensin


O-Desmethylangolensin is a metabolite of soy isoflavone, daidzein metabolized by gut microbiota. O-Desmethylangolensin possesses antioxidant activity[1][2].

 Names

Name 1-(2,4-dihydroxyphenyl)-2-(4-hydroxyphenyl)propan-1-one
Synonym More Synonyms

 O-Desmethylangolensin Biological Activity

Description O-Desmethylangolensin is a metabolite of soy isoflavone, daidzein metabolized by gut microbiota. O-Desmethylangolensin possesses antioxidant activity[1][2].
Related Catalog
Target

Human Endogenous Metabolite

In Vitro O-Desmethylangolensin (O-DMA) inhibits the growth of HepG2 cells at higher doses (~30% decrease at 75 μM)[2].
References

[1]. Elizabeth J Reverri, et al. Metabolomics reveals differences between three daidzein metabolizing phenotypes in adults with cardiometabolic risk factors. Mol Nutr Food Res. 2017 Jan;61(1).

[2]. Eun Jeong Choi, et al. The antioxidant activity of daidzein metabolites, O‑desmethylangolensin and equol, in HepG2 cells. Mol Med Rep. 2014 Jan;9(1):328-32.

 Chemical & Physical Properties

Density 1.329g/cm3
Boiling Point 483.3ºC at 760mmHg
Molecular Formula C15H14O4
Molecular Weight 258.26900
Flash Point 260.2ºC
Exact Mass 258.08900
PSA 77.76000
LogP 2.78980
Vapour Pressure 5.76E-10mmHg at 25°C
Index of Refraction 1.652
Storage condition 2-8°C

 Safety Information

HS Code 2914501900

 Synthetic Route

~82%

O-Desmethylangolensin Structure

O-Desmethylango...

CAS#:21255-69-6

Literature: Goto, Hideyuki; Terao, Yoshiyasu; Akai, Shuji Chemical and Pharmaceutical Bulletin, 2009 , vol. 57, # 4 p. 346 - 360

~40%

O-Desmethylangolensin Structure

O-Desmethylango...

CAS#:21255-69-6

Literature: Salakka; Waehaelae Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 18 p. 2601 - 2604

 Customs

HS Code 2914501900
Summary 2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

 Synonyms

O-Desmethylangolensin
o-demethylangolensin
O-Demethylangolesin