o-Iodohippurate sodium

Modify Date: 2025-08-27 17:18:08

o-Iodohippurate sodium structure	Common Name	o-Iodohippurate sodium
	CAS Number	133-17-5	Molecular Weight	327.05100
	Density	N/A	Boiling Point	480.9ºC at 760mmHg
	Molecular Formula	C₉H₇INNaO₃	Melting Point	N/A
	MSDS	N/A	Flash Point	244.6ºC

Use of o-Iodohippurate sodium

o-Iodohippurate sodium is an analogue of p-aminohippuric acid for the determination of effective renal plasma flow. Labelled OIH has a significantly higher clearance than other radiopharmaceutical yet developed and is eminently suitable for renography. It is eliminated mainly by tubular secretion. In patients with normally functioning kidneys, 85% of the OIH may be found in the urine 30 minutes after intravenous injection.

Name	sodium o-iodohippurate
Synonym	More Synonyms

Boiling Point	480.9ºC at 760mmHg
Molecular Formula	C₉H₇INNaO₃
Molecular Weight	327.05100
Flash Point	244.6ºC
Exact Mass	326.93700
PSA	69.23000
LogP	0.16180
Vapour Pressure	4.67E-10mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MR8162000

CHEMICAL NAME :: Hippuric acid, o-iodo-, monosodium salt

CAS REGISTRY NUMBER :: 133-17-5

LAST UPDATED :: 199309

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C9-H7-I-N-O3.Na

MOLECULAR WEIGHT :: 327.06

WISWESSER LINE NOTATION :: OVIMVR BI &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 116,394,1956

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 42,721,1953

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: MECHAN Medicinal Chemistry, A Series of Reviews. (New York, NY) V.1-6, 1951-63. Discontinued. Volume(issue)/page/year: 6,290,1963

hippuran

jodairol

iodohippura

medopaque

Sodium iodohippurate

EINECS 205-097-5

iodairal

renumbral

orthoiodin

iodohippuratesodium

hippodin

urocontrast

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o-Iodohippurate sodium

Use of o-Iodohippurate sodium

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.