lomefloxacin, aspartate

Modify Date: 2024-01-08 15:29:17

lomefloxacin, aspartate Structure
lomefloxacin, aspartate structure
Common Name lomefloxacin, aspartate
CAS Number 211690-33-4 Molecular Weight 484.451
Density N/A Boiling Point N/A
Molecular Formula C21H26F2N4O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of lomefloxacin, aspartate


Lomefloxacin (SC47111A) aspartate is a broad-spectrum quinolone antibacterial agent. Lomefloxacin aspartate can be used for researching respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc.[1][2].

 Names

Name (2S)-2-aminobutanedioic acid,1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
Synonym More Synonyms

 lomefloxacin, aspartate Biological Activity

Description Lomefloxacin (SC47111A) aspartate is a broad-spectrum quinolone antibacterial agent. Lomefloxacin aspartate can be used for researching respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc.[1][2].
Related Catalog
Target

MIC90: 0.12 mg/L (Haemophilus influenzae), 0.25 mg/L (Moraxella catarrhalis), 0.06 mg/L (Legionella pneumophila)[1]

References

[1]. Hoogkamp-Korstanje JA. In-vitro activities of ciprofloxacin, levofloxacin, lomefloxacin, ofloxacin, pefloxacin, sparfloxacin and trovafloxacin against gram-positive and gram-negative pathogens from respiratory tract infections. J Antimicrob Chemother. 1997 Sep;40(3):427-31.

[2]. Reem I Al-Wabli. Lomefloxacin. Profiles Drug Subst Excip Relat Methodol. 2017;42:193-240.

 Chemical & Physical Properties

Molecular Formula C21H26F2N4O7
Molecular Weight 484.451
Exact Mass 484.176941
PSA 175.19000
LogP 1.76300
Storage condition -20°C Freezer

 Synonyms

I06-2220
DM 10 L-Aspartate
(S)-2-Aminosuccinic acid 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (1:1)
3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-, compd. with L-aspartic acid (1:1)
Lomefloxacin Aspartate
1-Ethyl-6,8-difluoro-7-(3-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid - L-aspartic acid (1:1)