lomefloxacin, aspartate

Names

[ Name ]:
lomefloxacin, aspartate

[Synonym ]:
I06-2220
DM 10 L-Aspartate
(S)-2-Aminosuccinic acid 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (1:1)
3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-, compd. with L-aspartic acid (1:1)
Lomefloxacin Aspartate
1-Ethyl-6,8-difluoro-7-(3-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid - L-aspartic acid (1:1)

Biological Activity

[Description]:

Lomefloxacin (SC47111A) aspartate is a broad-spectrum quinolone antibacterial agent. Lomefloxacin aspartate can be used for researching respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc.[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

MIC90: 0.12 mg/L (Haemophilus influenzae), 0.25 mg/L (Moraxella catarrhalis), 0.06 mg/L (Legionella pneumophila)[1]

[References]

[1]. Hoogkamp-Korstanje JA. In-vitro activities of ciprofloxacin, levofloxacin, lomefloxacin, ofloxacin, pefloxacin, sparfloxacin and trovafloxacin against gram-positive and gram-negative pathogens from respiratory tract infections. J Antimicrob Chemother. 1997 Sep;40(3):427-31.

[2]. Reem I Al-Wabli. Lomefloxacin. Profiles Drug Subst Excip Relat Methodol. 2017;42:193-240.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₆F₂N₄O₇

[ Molecular Weight ]:
484.451

[ Exact Mass ]:
484.176941

[ PSA ]:
175.19000

[ LogP ]:
1.76300

[ Storage condition ]:
-20°C Freezer

Related Compounds

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