2,4-Difluorophenylethynylcobalamin

Modify Date: 2024-01-03 11:29:56

2,4-Difluorophenylethynylcobalamin structure	Common Name	2,4-Difluorophenylethynylcobalamin
	CAS Number	2101750-19-8	Molecular Weight	1466.45
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₇₀H₉₁CoF₂N₁₃O₁₄P	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2,4-Difluorophenylethynylcobalamin

2,4-Difluorophenylethynylcobalamin is a potential B12 antivitamin via binding to human B12 -processing enzyme CblC with high affinity (KD=130 nm). 2,4-Difluorophenylethynylcobalamin withstood tailoring by CblC, and stabilizes the ternary complex with the cosubstrate glutathione (GSH)[1].

Name	2,4-Difluorophenylethynylcobalamin

Description	2,4-Difluorophenylethynylcobalamin is a potential B12 antivitamin via binding to human B12 -processing enzyme CblC with high affinity (KD=130 nm). 2,4-Difluorophenylethynylcobalamin withstood tailoring by CblC, and stabilizes the ternary complex with the cosubstrate glutathione (GSH)[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
Target	B12 -processing enzyme CblC[1]
References	[1]. Ruetz M, et al. Antivitamin B12 Inhibition of the Human B12 -Processing Enzyme CblC: Crystal Structure of an Inactive Ternary Complex with Glutathione as the Cosubstrate. Angew Chem Int Ed Engl. 2017 Jun 19;56(26):7387-7392.

Molecular Formula	C₇₀H₉₁CoF₂N₁₃O₁₄P
Molecular Weight	1466.45

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

2,4-Difluorophenylethynylcobalamin

Use of 2,4-Difluorophenylethynylcobalamin

Names

2,4-Difluorophenylethynylcobalamin Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.