2,4-Difluorophenylethynylcobalamin

Modify Date: 2024-01-03 11:29:56

2,4-Difluorophenylethynylcobalamin structure	Common Name	2,4-Difluorophenylethynylcobalamin
	CAS Number	2101750-19-8	Molecular Weight	1466.45
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₇₀H₉₁CoF₂N₁₃O₁₄P	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2,4-Difluorophenylethynylcobalamin

2,4-Difluorophenylethynylcobalamin is a potential B12 antivitamin via binding to human B12 -processing enzyme CblC with high affinity (KD=130 nm). 2,4-Difluorophenylethynylcobalamin withstood tailoring by CblC, and stabilizes the ternary complex with the cosubstrate glutathione (GSH)[1].

Name	2,4-Difluorophenylethynylcobalamin

Description	2,4-Difluorophenylethynylcobalamin is a potential B12 antivitamin via binding to human B12 -processing enzyme CblC with high affinity (KD=130 nm). 2,4-Difluorophenylethynylcobalamin withstood tailoring by CblC, and stabilizes the ternary complex with the cosubstrate glutathione (GSH)[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
Target	B12 -processing enzyme CblC[1]
References	[1]. Ruetz M, et al. Antivitamin B12 Inhibition of the Human B12 -Processing Enzyme CblC: Crystal Structure of an Inactive Ternary Complex with Glutathione as the Cosubstrate. Angew Chem Int Ed Engl. 2017 Jun 19;56(26):7387-7392.

Molecular Formula	C₇₀H₉₁CoF₂N₁₃O₁₄P
Molecular Weight	1466.45

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2,4-Difluorophenylethynylcobalamin

Use of 2,4-Difluorophenylethynylcobalamin

Names

2,4-Difluorophenylethynylcobalamin Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.