JMI-346

Modify Date: 2024-04-06 13:57:27

JMI-346 structure	Common Name	JMI-346
	CAS Number	2091841-46-0	Molecular Weight	336.39
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₂₀N₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of JMI-346

JMI-346 is a potent PfFP-2 (Plasmodium falciparum falcipain-2 protease) inhibitor. JMI-346 inhibits the growth of CQS (3D7; IC50=13 µM) and CQR (RKL-9; IC50=33 µM) strains of P. falciparum. JMI-346 has the potential to be used as an anti-malarial agent[1].

Name	JMI-346

Description	JMI-346 is a potent PfFP-2 (Plasmodium falciparum falcipain-2 protease) inhibitor. JMI-346 inhibits the growth of CQS (3D7; IC50=13 µM) and CQR (RKL-9; IC50=33 µM) strains of P. falciparum. JMI-346 has the potential to be used as an anti-malarial agent[1].
Related Catalog	Research Areas >> Infection
References	[1]. Uddin A, et al. Identification and structure-activity relationship (SAR) studies of carvacrol derivatives as potential anti-malarial against Plasmodium falciparum falcipain-2 protease. Bioorg Chem. 2020 Oct;103:104142.

Molecular Formula	C₁₉H₂₀N₄O₂
Molecular Weight	336.39

JMI-346

Use of JMI-346

Names

JMI-346 Biological Activity

Chemical & Physical Properties