2091841-46-0

2091841-46-0 structure

Name: JMI-346
Chemical Name: JMI-346
CAS Number: 2091841-46-0
Molecular Formula: C₁₉H₂₀N₄O₂
Molecular Weight: 336.39
Catalog: Research Areas Infection
Create Date: 2022-08-18 06:39:13
Modify Date: 2024-04-06 13:57:27
JMI-346 is a potent PfFP-2 (Plasmodium falciparum falcipain-2 protease) inhibitor. JMI-346 inhibits the growth of CQS (3D7; IC50=13 µM) and CQR (RKL-9; IC50=33 µM) strains of P. falciparum. JMI-346 has the potential to be used as an anti-malarial agent[1].

Name	JMI-346

Description	JMI-346 is a potent PfFP-2 (Plasmodium falciparum falcipain-2 protease) inhibitor. JMI-346 inhibits the growth of CQS (3D7; IC50=13 µM) and CQR (RKL-9; IC50=33 µM) strains of P. falciparum. JMI-346 has the potential to be used as an anti-malarial agent[1].
Related Catalog	Research Areas >> Infection
References	[1]. Uddin A, et al. Identification and structure-activity relationship (SAR) studies of carvacrol derivatives as potential anti-malarial against Plasmodium falciparum falcipain-2 protease. Bioorg Chem. 2020 Oct;103:104142.

Molecular Formula	C₁₉H₂₀N₄O₂
Molecular Weight	336.39