GLL398
Modify Date: 2024-09-03 20:07:06
GLL398 structure
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Common Name | GLL398 | ||
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| CAS Number | 2077980-80-2 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GLL398GLL398, an orally active selective estrogen receptor degrader (SERD), competitively binds to the estrogen receptor with an IC50 value of 1.14 nM. GLL398 exhibits a strong dose-dependent binding profile for the ER with a Y537S point mutation (IC50= 29.5 nM). GLL398 blocks tumor growth in xenograft breast cancer models[1]. |
| Name | GLL398 |
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| Description | GLL398, an orally active selective estrogen receptor degrader (SERD), competitively binds to the estrogen receptor with an IC50 value of 1.14 nM. GLL398 exhibits a strong dose-dependent binding profile for the ER with a Y537S point mutation (IC50= 29.5 nM). GLL398 blocks tumor growth in xenograft breast cancer models[1]. |
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| Related Catalog | |
| In Vitro | GLL398 is a boron-modified GW5638 analog[1]. |
| References |
| No Any Chemical & Physical Properties |