Rovanersen
Modify Date: 2024-01-14 22:41:08
Rovanersen structure
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Common Name | Rovanersen | ||
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| CAS Number | 2072901-32-5 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of RovanersenRovanersen (WVE-120101) is an antisense oligonucleotide that can be used for huntington’s disease research[1]. |
| Name | Rovanersen |
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| Description | Rovanersen (WVE-120101) is an antisense oligonucleotide that can be used for huntington’s disease research[1]. |
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| Related Catalog | |
| In Vitro | In vitro, Rovanersen (WVE-120101) leads to the selective RNase H cleavage of mutant Huntingtin allele (mHTT) over wtHTT, with no complement activation. Rovanersen selectively decreases mHTT mRNA and protein levels compared with wtHTT in multiple cells lines[1]. |
| In Vivo | In non-human primates (NHPs), Rovanersen (WVE-120101) is found in nuclear and perinuclear compartments of neurons in brain areas believed to be involved in HD pathology[1]. |
| References |
| No Any Chemical & Physical Properties |