HCV-IN-4

Modify Date: 2025-08-25 21:55:57

HCV-IN-4 Structure
HCV-IN-4 structure
Common Name HCV-IN-4
CAS Number 2058080-25-2 Molecular Weight 956.07
Density N/A Boiling Point N/A
Molecular Formula C52H58FN9O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HCV-IN-4


HCV-IN-4 is a potent and orally active HCV NS5A inhibitor, shows great potency against GT1a, GT2b, GT3a, GT1a Y93H and GT1a L31V, with EC90s of 3 pM, 0.3 nM, 0.01 nM, 0.5 nM and 0.02 nM, respectively[1].

 Names

Name HCV-IN-4

 HCV-IN-4 Biological Activity

Description HCV-IN-4 is a potent and orally active HCV NS5A inhibitor, shows great potency against GT1a, GT2b, GT3a, GT1a Y93H and GT1a L31V, with EC90s of 3 pM, 0.3 nM, 0.01 nM, 0.5 nM and 0.02 nM, respectively[1].
Related Catalog
Target

EC90: 3 pM (GT1a), 0.3 nM (GT2b), 0.01 nM (GT3a), 0.5 nM (GT1a Y93H), 0.02 nM (GT1a L31V)[1]

References

[1]. Yu W, et al. Discovery of Chromane Containing Hepatitis C Virus (HCV) NS5A Inhibitors with Improved Potency against Resistance-Associated Variants. J Med Chem. 2016 Nov 23;59(22):10228-10243. Epub 2016 Nov 9.

 Chemical & Physical Properties

Molecular Formula C52H58FN9O8
Molecular Weight 956.07
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