2058080-25-2

2058080-25-2 structure
2058080-25-2 structure
  • Name: HCV-IN-4
  • Chemical Name: HCV-IN-4
  • CAS Number: 2058080-25-2
  • Molecular Formula: C52H58FN9O8
  • Molecular Weight: 956.07
  • Catalog: Signaling Pathways Anti-infection HCV
  • Create Date: 2019-08-04 15:33:58
  • Modify Date: 2024-01-09 23:52:43
  • HCV-IN-4 is a potent and orally active HCV NS5A inhibitor, shows great potency against GT1a, GT2b, GT3a, GT1a Y93H and GT1a L31V, with EC90s of 3 pM, 0.3 nM, 0.01 nM, 0.5 nM and 0.02 nM, respectively[1].

Name HCV-IN-4
Description HCV-IN-4 is a potent and orally active HCV NS5A inhibitor, shows great potency against GT1a, GT2b, GT3a, GT1a Y93H and GT1a L31V, with EC90s of 3 pM, 0.3 nM, 0.01 nM, 0.5 nM and 0.02 nM, respectively[1].
Related Catalog
Target

EC90: 3 pM (GT1a), 0.3 nM (GT2b), 0.01 nM (GT3a), 0.5 nM (GT1a Y93H), 0.02 nM (GT1a L31V)[1]

References

[1]. Yu W, et al. Discovery of Chromane Containing Hepatitis C Virus (HCV) NS5A Inhibitors with Improved Potency against Resistance-Associated Variants. J Med Chem. 2016 Nov 23;59(22):10228-10243. Epub 2016 Nov 9.

Molecular Formula C52H58FN9O8
Molecular Weight 956.07