PC Methyltetrazine-PEG4-NHS carbonate ester

Modify Date: 2025-08-27 19:41:07

PC Methyltetrazine-PEG4-NHS carbonate ester structure	Common Name	PC Methyltetrazine-PEG4-NHS carbonate ester
	CAS Number	2055736-28-0	Molecular Weight	785.75
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₅H₄₃N₇O₁₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PC Methyltetrazine-PEG4-NHS carbonate ester

PC Methyltetrazine-PEG4-NHS carbonate ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	PC Methyltetrazine-PEG4-NHS carbonate ester

Description	PC Methyltetrazine-PEG4-NHS carbonate ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₃₅H₄₃N₇O₁₄
Molecular Weight	785.75
InChIKey	FYXJZLYXHCHOII-UHFFFAOYSA-N
SMILES	COc1cc(C(C)OC(=O)ON2C(=O)CCC2=O)c([N+](=O)[O-])cc1OCCCC(=O)NCCOCCOCCOCCOc1ccc(-c2nnc(C)nn2)cc1

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