Dde Biotin-PEG4-Picolyl azide

Modify Date: 2024-01-10 18:54:15

Dde Biotin-PEG4-Picolyl azide Structure
Dde Biotin-PEG4-Picolyl azide structure
Common Name Dde Biotin-PEG4-Picolyl azide
CAS Number 2055048-42-3 Molecular Weight 815.98
Density N/A Boiling Point N/A
Molecular Formula C38H57N9O9S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Dde Biotin-PEG4-Picolyl azide


Dde Biotin-PEG4-Picolyl azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Dde Biotin-PEG4-Picolyl azide

 Dde Biotin-PEG4-Picolyl azide Biological Activity

Description Dde Biotin-PEG4-Picolyl azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C38H57N9O9S
Molecular Weight 815.98