Vanin-1-IN-2

Modify Date: 2025-09-05 01:02:32

Vanin-1-IN-2 Structure
Vanin-1-IN-2 structure
Common Name Vanin-1-IN-2
CAS Number 2054952-13-3 Molecular Weight 296.35
Density N/A Boiling Point N/A
Molecular Formula C15H12N4OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Vanin-1-IN-2


Vanin-1-IN-2 is a potent vanin-1 inhibitor with an IC50 of 162 nM. Vanin-1 is a cell-surface-associated, glycosylphosphatidyl inositol (GPI)-anchored protein which is expressed at high levels in the kidney, liver, and small intestine[1].

 Names

Name Vanin-1-IN-2

 Vanin-1-IN-2 Biological Activity

Description Vanin-1-IN-2 is a potent vanin-1 inhibitor with an IC50 of 162 nM. Vanin-1 is a cell-surface-associated, glycosylphosphatidyl inositol (GPI)-anchored protein which is expressed at high levels in the kidney, liver, and small intestine[1].
Related Catalog
References

[1]. Casimiro-Garcia A, et al. Discovery of a Series of Pyrimidine Carboxamides as Inhibitors of Vanin-1. J Med Chem. 2022;65(1):757-784.

 Chemical & Physical Properties

Molecular Formula C15H12N4OS
Molecular Weight 296.35
InChIKey XXQGGYNRNJTVTN-UHFFFAOYSA-N
SMILES O=C(c1cnc(NCc2cccnc2)nc1)c1cccs1
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