HDAC3 Inhibitor (Histone Deacetylase 3)

Modify Date: 2024-01-14 12:24:33

HDAC3 Inhibitor (Histone Deacetylase 3) Structure
HDAC3 Inhibitor (Histone Deacetylase 3) structure
Common Name HDAC3 Inhibitor (Histone Deacetylase 3)
CAS Number 2044701-99-5 Molecular Weight 337.42
Density 1.140±0.06 g/cm3(Predicted) Boiling Point 562.5±50.0 °C(Predicted)
Molecular Formula C20H23N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HDAC3 Inhibitor (Histone Deacetylase 3)


HDAC3-IN-1 (compound 5) is a potent and selective HDAC3 inhibitor, with an IC50 of 5.96 nM[1].

 Names

Name HDAC3 Inhibitor

 HDAC3 Inhibitor (Histone Deacetylase 3) Biological Activity

Description HDAC3-IN-1 (compound 5) is a potent and selective HDAC3 inhibitor, with an IC50 of 5.96 nM[1].
Related Catalog
Target

HDAC3:5.96 ± 0.0 nM (IC50)

HDAC1:36.4 ± 0.2 nM (IC50)

HDAC2:89.9 ± 0.7 nM (IC50)

References

[1]. Moreno-Yruela C, Olsen CA. Determination of Slow-Binding HDAC Inhibitor Potency and Subclass Selectivity. ACS Med Chem Lett. 2022 Mar 16;13(5):779-785.

 Chemical & Physical Properties

Density 1.140±0.06 g/cm3(Predicted)
Boiling Point 562.5±50.0 °C(Predicted)
Molecular Formula C20H23N3O2
Molecular Weight 337.42