IDO/TDO-IN-1

Modify Date: 2025-08-24 23:05:53

IDO/TDO-IN-1 Structure
IDO/TDO-IN-1 structure
 Common Name IDO/TDO-IN-1
CAS Number 2033173-01-0 Molecular Weight 413.49
Density N/A Boiling Point N/A
Molecular Formula C25H24FN5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IDO/TDO-IN-1


IDO/TDO-IN-1 (compound 25) is a highly potent and orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor with IC50s of 9.7 and 47 nM, respectively [1].

 Names

Name IDO/TDO-IN-1

 IDO/TDO-IN-1 Biological Activity

Description IDO/TDO-IN-1 (compound 25) is a highly potent and orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor with IC50s of 9.7 and 47 nM, respectively [1].
Related Catalog
Target

IC50: 9.7 nM (Indoleamine-2,3-dioxygenase), 47 nM (Tryptophan 2,3-dioxygenase)[1]

In Vitro IDO/TDO-IN-1 inhibits IDO in the Hela cell line with an IC50 of 76 nM[1].
References

[1]. Tu W, et al. Discovery of Imidazoisoindole Derivatives as Highly Potent and Orally Active Indoleamine-2,3-dioxygenase Inhibitors. ACS Med Chem Lett. 2019 Jun 3;10(6):949-953.

 Chemical & Physical Properties

Molecular Formula C25H24FN5
Molecular Weight 413.49
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Chemsrc provides IDO/TDO-IN-1(CAS#:2033173-01-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of IDO/TDO-IN-1 are included as well.>> amp version: IDO/TDO-IN-1

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