1402837-76-6

1402837-76-6 structure

Name: IDO-IN-6
Chemical Name: IDO-IN-6
CAS Number: 1402837-76-6
Molecular Formula: C₁₈H₂₁FN₂O₂
Molecular Weight: 316.370
Catalog: Signaling Pathways Metabolic Enzyme/Protease Indoleamine 2,3-Dioxygenase (IDO)
Create Date: 2018-04-21 03:39:58
Modify Date: 2025-08-27 17:08:31
IDO-IN-6 (NLG-1486) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, Compound 1486, has an IC50 of <1 μM.

Name	IDO-IN-6
Synonyms	5H-Imidazo[5,1-a]isoindole-5-ethanol, 6-fluoro-α-(trans-4-hydroxycyclohexyl)-, (αS,5S)- trans-4-{(1S)-2-[(5S)-6-Fluoro-5H-imidazo[5,1-a]isoindol-5-yl]-1-hydroxyethyl}cyclohexanol

Description	IDO-IN-6 (NLG-1486) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, Compound 1486, has an IC50 of <1 μM.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Indoleamine 2,3-Dioxygenase (IDO) Research Areas >> Cancer
Target	IDO:1 μM (IC50)
In Vitro	IDO-IN-6 (Compound 1486) is an indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of <1 μM (this is the concentration of IDO-IN-6 at which inhibits 50% of enzymatic activity using recombinant human IDO)[1].
References	[1]. Mautino, et al. Preparation of fused imidazole derivatives as IDO inhibitors. From PCT Int. Appl. (2012), 20121018.