(±)-Coclaurine

Modify Date: 2024-01-23 10:05:59

(±)-Coclaurine Structure
(±)-Coclaurine structure
Common Name (±)-Coclaurine
CAS Number 2033-08-1 Molecular Weight 285.33800
Density N/A Boiling Point N/A
Molecular Formula C17H19NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (±)-Coclaurine


(±)-Coclaurine is a natural product that can be found in Roemeria refracta. (±)-Coclaurine exhibits antioxidative activity and cardiovascular effects[1][2][3].

 Names

Name coclaurine
Synonym More Synonyms

 (±)-Coclaurine Biological Activity

Description (±)-Coclaurine is a natural product that can be found in Roemeria refracta. (±)-Coclaurine exhibits antioxidative activity and cardiovascular effects[1][2][3].
Related Catalog
In Vitro (±)-Coclaurine (1 μM-1 mM) 以浓度依赖性方式松弛 KCl 诱导的主动脉环收缩[3]。
References

[1]. Gözler B, et, al. Epimeric Isopavine N-Oxides from Roemeria refracta. Phytotherapy Research. Helvetica. 1992 Feb 5; 75(1): 260-268.

[2]. Cassels BK, et, al. Structure-antioxidative activity relationships in benzylisoquinoline alkaloids. Pharmacol Res. 1995 Feb;31(2):103-7.  

[3]. Morales MA, et, al. Cardiovascular effects of plant secondary metabolites norarmepavine, coclaurine and norcoclaurine. Phytotherapy Research. 1998 Mar; 12(2): 103-109.

 Chemical & Physical Properties

Molecular Formula C17H19NO3
Molecular Weight 285.33800
Exact Mass 285.13600
PSA 61.72000
LogP 2.86470

 Synonyms

1-(4-hydroxy-benzyl)-6-methoxy-1,2,3,4-tetrahydro-isoquinolin-7-ol
D,L-coclaurine
dl-coclaurine
(R,S)-coclaurine
(+/-)-coclaurine
1-(4-Hydroxy-benzyl)-6-methoxy-1,2,3,4-tetrahydro-isoquinolin-7-ol
(+/-)-Coclaurine