t-Boc-Aminooxy-PEG4-CH2CO2H

Modify Date: 2024-01-19 17:59:47

t-Boc-Aminooxy-PEG4-CH2CO2H Structure
t-Boc-Aminooxy-PEG4-CH2CO2H structure
Common Name t-Boc-Aminooxy-PEG4-CH2CO2H
CAS Number 2028281-90-3 Molecular Weight 367.39
Density N/A Boiling Point N/A
Molecular Formula C15H29NO9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of t-Boc-Aminooxy-PEG4-CH2CO2H


Boc-Aminooxy-PEG4-CH2CO2H is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Boc-Aminooxy-PEG4-CH2CO2H
Synonym More Synonyms

 t-Boc-Aminooxy-PEG4-CH2CO2H Biological Activity

Description Boc-Aminooxy-PEG4-CH2CO2H is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413.

 Chemical & Physical Properties

Molecular Formula C15H29NO9
Molecular Weight 367.39

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD30458018