t-Boc-Aminooxy-PEG4-azide

Modify Date: 2024-01-27 18:51:16

t-Boc-Aminooxy-PEG4-azide Structure
t-Boc-Aminooxy-PEG4-azide structure
Common Name t-Boc-Aminooxy-PEG4-azide
CAS Number 2100306-64-5 Molecular Weight 378.42
Density N/A Boiling Point N/A
Molecular Formula C15H30N4O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of t-Boc-Aminooxy-PEG4-azide


Boc-Aminooxy-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Boc-Aminooxy-PEG4-azide

 t-Boc-Aminooxy-PEG4-azide Biological Activity

Description Boc-Aminooxy-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413.

 Chemical & Physical Properties

Molecular Formula C15H30N4O7
Molecular Weight 378.42