REV7/REV3L-IN-1

Modify Date: 2025-09-23 11:13:22

REV7/REV3L-IN-1 Structure
REV7/REV3L-IN-1 structure
Common Name REV7/REV3L-IN-1
CAS Number 1979192-13-6 Molecular Weight 371.45
Density N/A Boiling Point N/A
Molecular Formula C19H21N3O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of REV7/REV3L-IN-1


REV7/REV3L-IN-1 is a REV7/REV3L interaction inhibitor with an IC50 of 78 μM, which directly binds to REV7 in nuclear magnetic resonance analyses, and inhibits the reactivation of a reporter plasmid containing an interstrand crosslink (ICL) in between the promoter and reporter regions[1].

 Names

Name REV7/REV3L-IN-1

 REV7/REV3L-IN-1 Biological Activity

Description REV7/REV3L-IN-1 is a REV7/REV3L interaction inhibitor with an IC50 of 78 μM, which directly binds to REV7 in nuclear magnetic resonance analyses, and inhibits the reactivation of a reporter plasmid containing an interstrand crosslink (ICL) in between the promoter and reporter regions[1].
Related Catalog
Target

IC50: 78 μM (REV7/REV3L interaction)[1]

References

[1]. Actis ML, et al. Identification of the first small-molecule inhibitor of the REV7 DNA repair protein interaction. Bioorg Med Chem. 2016 Sep 15;24(18):4339-4346.

 Chemical & Physical Properties

Molecular Formula C19H21N3O3S
Molecular Weight 371.45
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