1979192-13-6

1979192-13-6 structure

Name: REV7/REV3L-IN-1
Chemical Name: REV7/REV3L-IN-1
CAS Number: 1979192-13-6
Molecular Formula: C₁₉H₂₁N₃O₃S
Molecular Weight: 371.45
Catalog: Research Areas Cancer
Create Date: 2019-08-03 18:18:59
Modify Date: 2024-02-05 08:31:40
REV7/REV3L-IN-1 is a REV7/REV3L interaction inhibitor with an IC50 of 78 μM, which directly binds to REV7 in nuclear magnetic resonance analyses, and inhibits the reactivation of a reporter plasmid containing an interstrand crosslink (ICL) in between the promoter and reporter regions[1].

Name	REV7/REV3L-IN-1

Description	REV7/REV3L-IN-1 is a REV7/REV3L interaction inhibitor with an IC50 of 78 μM, which directly binds to REV7 in nuclear magnetic resonance analyses, and inhibits the reactivation of a reporter plasmid containing an interstrand crosslink (ICL) in between the promoter and reporter regions[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	IC50: 78 μM (REV7/REV3L interaction)[1]
References	[1]. Actis ML, et al. Identification of the first small-molecule inhibitor of the REV7 DNA repair protein interaction. Bioorg Med Chem. 2016 Sep 15;24(18):4339-4346.

Molecular Formula	C₁₉H₂₁N₃O₃S
Molecular Weight	371.45