CD 3254

Modify Date: 2024-01-04 19:20:18

CD 3254 Structure
CD 3254 structure
Common Name CD 3254
CAS Number 196961-43-0 Molecular Weight 364.47700
Density N/A Boiling Point N/A
Molecular Formula C24H28O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CD 3254


CD3254 a potent and selective retinoid-X-receptor (RXR) agonist[1].

 Names

Name 3-[4-hydroxy-3-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)phenyl]prop-2-enoic acid

 CD 3254 Biological Activity

Description CD3254 a potent and selective retinoid-X-receptor (RXR) agonist[1].
Related Catalog
Target

RXR

In Vitro CD3254 induces similar phenotypes of malformations after 5 days exposure at low concentration (20 μg/L) to those after the 1st d exposure at high concentrations (50 and 100 μg/L)[1]. Cell Viability Assay[1] Cell Line: zebrafish (Danio rerio) embryos Concentration: 10, 20, 50, 100 μg/L Incubation Time: Result: The percent of survival decreased by 19.1 % in 100 μg/L CD3254-treated group after the 1st day exposure. The embryos did not hatch in groups exposed to 100 μg/L CD3254 for 5 days or to 1 mg/L CD3254 for the 1st day.
References

[1]. Nahoum V, et al. Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function. Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17323-8.

 Chemical & Physical Properties

Molecular Formula C24H28O3
Molecular Weight 364.47700
Exact Mass 364.20400
PSA 57.53000
LogP 5.81440