Pomalidomide-C2-NH2(E3 ligase Ligand 17)

Modify Date: 2024-01-10 15:34:44

Pomalidomide-C2-NH2(E3 ligase Ligand 17) Structure
Pomalidomide-C2-NH2(E3 ligase Ligand 17) structure
Common Name Pomalidomide-C2-NH2(E3 ligase Ligand 17)
CAS Number 1957235-66-3 Molecular Weight 316.31
Density N/A Boiling Point N/A
Molecular Formula C15H16N4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pomalidomide-C2-NH2(E3 ligase Ligand 17)


E3 ligase Ligand 17 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 17 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].

 Names

Name E3 ligase Ligand 17

 Pomalidomide-C2-NH2(E3 ligase Ligand 17) Biological Activity

Description E3 ligase Ligand 17 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 17 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
Related Catalog
References

[1]. Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.

 Chemical & Physical Properties

Molecular Formula C15H16N4O4
Molecular Weight 316.31

 Safety Information

Hazard Codes Xi