SJ-3366

Modify Date: 2025-08-25 20:15:48

SJ-3366 structure	Common Name	SJ-3366
	CAS Number	195720-26-4	Molecular Weight	352.42700
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₄N₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SJ-3366

SJ-3366 (IQP-0410) is a potent inhibitor of HIV nonnucleoside reverse transcriptase[1]. SJ-3366 (IQP-0410) inhibits HIV at sub-nanomolar concentrations primarily through a typical non-nucleoside mechanism[2].

Name	1-(cyclopent-3-en-1-ylmethyl)-6-(3,5-dimethylbenzoyl)-5-ethylpyrimidine-2,4-dione
Synonym	More Synonyms

Description	SJ-3366 (IQP-0410) is a potent inhibitor of HIV nonnucleoside reverse transcriptase[1]. SJ-3366 (IQP-0410) inhibits HIV at sub-nanomolar concentrations primarily through a typical non-nucleoside mechanism[2].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Inflammation/Immunology
Target	nonnucleoside reverse transcriptase[1]
References	[1]. Ham AS, Lustig W, Yang L, Boczar A, Buckheit KW, Buckheit RW Jr. In vitro and ex vivo evaluations on transdermal delivery of the HIV inhibitor IQP-0410. PLoS One. 2013;8(9):e75306. [2]. Buckheit RW Jr, Watson Buckheit K, Sturdevant CB, Buckheit RW 3rd. Selection and characterization of viruses resistant to the dual acting pyrimidinedione entry and non-nucleoside reverse transcriptase inhibitor IQP-0410. Antiviral Res. 2013;100(2):382-391.

Molecular Formula	C₂₁H₂₄N₂O₃
Molecular Weight	352.42700
Exact Mass	352.17900
PSA	72.19000
LogP	3.32530

Hazard Codes	Xi

IQP0410

Nab 2F5

Nab 2G12

SJ-3366

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SJ-3366

Use of SJ-3366

Names

SJ-3366 Biological Activity

Chemical & Physical Properties

Safety Information

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.