CDK9-IN-12

Modify Date: 2025-08-26 17:58:08

CDK9-IN-12 Structure
CDK9-IN-12 structure
Common Name CDK9-IN-12
CAS Number 1942843-54-0 Molecular Weight 378.85
Density N/A Boiling Point N/A
Molecular Formula C21H19ClN4O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CDK9-IN-12


CDK9-IN-12 displays the optimal CDK9 inhibitory activity with an IC50 value of 5.41 nM.

 Names

Name CDK9-IN-12

 CDK9-IN-12 Biological Activity

Description CDK9-IN-12 displays the optimal CDK9 inhibitory activity with an IC50 value of 5.41 nM.
Related Catalog
Target

CDK9/cyclinT1:5.41 nM (IC50)

References

[1]. Han X, et al. Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia. J Med Chem. 2021 Oct 14;64(19):14647-14663.

 Chemical & Physical Properties

Molecular Formula C21H19ClN4O
Molecular Weight 378.85
InChIKey SHDGEOLPEYTGCG-FQEVSTJZSA-N
SMILES Cc1[nH]nc2ccc(-c3cc(NC(CO)c4ccccc4)cnc3Cl)cc12
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