3542-63-0

3542-63-0 structure

3542-63-0 structure

Name: CDK9-IN-10
Chemical Name: 7-benzyloxy-5,8-dihydroxy-2-phenyl-chromen-4-one
CAS Number: 3542-63-0
Molecular Formula: C₂₂H₁₆O₅
Molecular Weight: 360.35900
Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
Create Date: 2017-06-06 16:23:45
Modify Date: 2024-01-14 08:53:13
CDK9-IN-10 is a potent CDK9 inhibitor. CDK9-IN-10 is the ligand for the PROTAC CDK9 degrader-2 (HY-112811)[1].

Name	7-benzyloxy-5,8-dihydroxy-2-phenyl-chromen-4-one
Synonyms	7-Benzyloxy-5,8-dihydroxy-2-phenyl-chromen-4-on 7-Benzyloxy-5,8-dihydroxy-flavon

Description	CDK9-IN-10 is a potent CDK9 inhibitor. CDK9-IN-10 is the ligand for the PROTAC CDK9 degrader-2 (HY-112811)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> CDK
Target	CDK9
References	[1]. Bian J, et al. Discovery of Wogonin-based PROTACs against CDK9 and capable of achieving antitumor activity. Bioorg Chem. 2018 Dec;81:373-381.

Molecular Formula	C₂₂H₁₆O₅
Molecular Weight	360.35900
Exact Mass	360.10000
PSA	79.90000
LogP	4.45020

Hazard Codes	Xi
HS Code	2914509090

Precursor 0
DownStream 2
632-85-9 3316-54-9

HS Code	2914509090
Summary	HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%