NH-(PEG2-acid)2

Modify Date: 2024-01-08 12:15:45

NH-(PEG2-acid)2 Structure
NH-(PEG2-acid)2 structure
Common Name NH-(PEG2-acid)2
CAS Number 1919044-99-7 Molecular Weight 337.37
Density N/A Boiling Point N/A
Molecular Formula C14H27NO8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NH-(PEG2-acid)2


NH-bis(PEG2-C2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name NH-bis(PEG2-C2-acid)
Synonym More Synonyms

 NH-(PEG2-acid)2 Biological Activity

Description NH-bis(PEG2-C2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C14H27NO8
Molecular Weight 337.37

 Synonyms

MFCD29912839