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1919044-99-7

1919044-99-7 structure
1919044-99-7 structure
  • Name: NH-(PEG2-acid)2
  • Chemical Name: NH-bis(PEG2-C2-acid)
  • CAS Number: 1919044-99-7
  • Molecular Formula: C14H27NO8
  • Molecular Weight: 337.37
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 14:23:24
  • Modify Date: 2024-01-08 12:15:45
  • NH-bis(PEG2-C2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name NH-bis(PEG2-C2-acid)
Synonyms MFCD29912839
Description NH-bis(PEG2-C2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C14H27NO8
Molecular Weight 337.37