MONIRO-1

Modify Date: 2024-01-14 00:53:47

MONIRO-1 structure	Common Name	MONIRO-1
	CAS Number	1909225-94-0	Molecular Weight	458.91
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₄ClFN₄O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MONIRO-1

MONIRO-1 is a T-type and N-type calcium channel blocker with IC50 values of 34, 3.3, 1.7 and 7.2 µM against hCav2.2, hCav3.1, hCav3.2 and hCav3.3, respectively[1].

Name	MONIRO-1

Description	MONIRO-1 is a T-type and N-type calcium channel blocker with IC50 values of 34, 3.3, 1.7 and 7.2 µM against hCav2.2, hCav3.1, hCav3.2 and hCav3.3, respectively[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Research Areas >> Neurological Disease
Target	Cav3.1:3.3 μM (IC50) Cav3.2:1.7 μM (IC50) Cav3.3:7.2 μM (IC50) Cav2.2:34 μM (IC50)
References	[1]. McArthur JR, et al. Inhibition of human N- and T-type calcium channels by an ortho-phenoxyanilide derivative, MONIRO-1. Br J Pharmacol. 2018 Jun;175(12):2284-2295.

Molecular Formula	C₂₃H₂₄ClFN₄O₃
Molecular Weight	458.91