1909225-94-0

1909225-94-0 structure
1909225-94-0 structure
  • Name: MONIRO-1
  • Chemical Name: MONIRO-1
  • CAS Number: 1909225-94-0
  • Molecular Formula: C23H24ClFN4O3
  • Molecular Weight: 458.91
  • Catalog: Signaling Pathways Membrane Transporter/Ion Channel Calcium Channel
  • Create Date: 2022-07-15 09:06:00
  • Modify Date: 2024-01-14 00:53:47
  • MONIRO-1 is a T-type and N-type calcium channel blocker with IC50 values of 34, 3.3, 1.7 and 7.2 µM against hCav2.2, hCav3.1, hCav3.2 and hCav3.3, respectively[1].

Name MONIRO-1
Description MONIRO-1 is a T-type and N-type calcium channel blocker with IC50 values of 34, 3.3, 1.7 and 7.2 µM against hCav2.2, hCav3.1, hCav3.2 and hCav3.3, respectively[1].
Related Catalog
Target

Cav3.1:3.3 μM (IC50)

Cav3.2:1.7 μM (IC50)

Cav3.3:7.2 μM (IC50)

Cav2.2:34 μM (IC50)

References

[1]. McArthur JR, et al. Inhibition of human N- and T-type calcium channels by an ortho-phenoxyanilide derivative, MONIRO-1. Br J Pharmacol. 2018 Jun;175(12):2284-2295.

Molecular Formula C23H24ClFN4O3
Molecular Weight 458.91
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