t-Boc-Aminooxy-PEG3-thiol

Modify Date: 2024-01-09 08:57:00

t-Boc-Aminooxy-PEG3-thiol Structure
t-Boc-Aminooxy-PEG3-thiol structure
Common Name t-Boc-Aminooxy-PEG3-thiol
CAS Number 1895922-75-4 Molecular Weight 325.42
Density N/A Boiling Point N/A
Molecular Formula C13H27NO6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of t-Boc-Aminooxy-PEG3-thiol


Boc-Aminooxy-PEG3-thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Boc-Aminooxy-PEG3-thiol
Synonym More Synonyms

 t-Boc-Aminooxy-PEG3-thiol Biological Activity

Description Boc-Aminooxy-PEG3-thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C13H27NO6S
Molecular Weight 325.42

 Synonyms

MFCD29764338
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