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1895922-75-4

1895922-75-4 structure
1895922-75-4 structure
  • Name: t-Boc-Aminooxy-PEG3-thiol
  • Chemical Name: Boc-Aminooxy-PEG3-thiol
  • CAS Number: 1895922-75-4
  • Molecular Formula: C13H27NO6S
  • Molecular Weight: 325.42
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 14:03:00
  • Modify Date: 2024-01-09 08:57:00
  • Boc-Aminooxy-PEG3-thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Boc-Aminooxy-PEG3-thiol
Synonyms MFCD29764338
Description Boc-Aminooxy-PEG3-thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C13H27NO6S
Molecular Weight 325.42
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