t-Boc-aminooxy-PEG6-propargyl

Modify Date: 2024-01-09 21:30:22

t-Boc-aminooxy-PEG6-propargyl Structure
t-Boc-aminooxy-PEG6-propargyl structure
Common Name t-Boc-aminooxy-PEG6-propargyl
CAS Number 2093152-83-9 Molecular Weight 435.51
Density N/A Boiling Point N/A
Molecular Formula C20H37NO9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of t-Boc-aminooxy-PEG6-propargyl


t-Boc-aminooxy-PEG6-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name t-Boc-aminooxy-PEG6-propargyl
Synonym More Synonyms

 t-Boc-aminooxy-PEG6-propargyl Biological Activity

Description t-Boc-aminooxy-PEG6-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C20H37NO9
Molecular Weight 435.51

 Synonyms

MFCD30723289