L 760735
Modify Date: 2024-01-09 09:43:27
L 760735 structure
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Common Name | L 760735 | ||
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| CAS Number | 188923-01-5 | Molecular Weight | 611.98 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H29ClF7N5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of L 760735L-760735 is a high affinity, selective and orally active NK1 receptor antagonist with an IC50 of 0.19 nM for human NK1 receptors. L-760735 exhibits anxiolytic and antidepressant-like effects[1]. |
| Name | 1-[5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-2H-triazol-4-yl]-N,N-dimethylmethanamine,hydrochloride |
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| Description | L-760735 is a high affinity, selective and orally active NK1 receptor antagonist with an IC50 of 0.19 nM for human NK1 receptors. L-760735 exhibits anxiolytic and antidepressant-like effects[1]. |
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| Related Catalog | |
| Target |
hNK1:0.19 nM (IC50) |
| References |
| Molecular Formula | C26H29ClF7N5O2 |
|---|---|
| Molecular Weight | 611.98 |
| Exact Mass | 611.19000 |
| PSA | 66.51000 |
| LogP | 6.46030 |