HX 531
Modify Date: 2025-09-11 11:52:43
HX 531 structure
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Common Name | HX 531 | ||
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| CAS Number | 188844-34-0 | Molecular Weight | 483.55800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H29N3O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of HX 531HX531 is a potent RXR antagonist with an IC50 of 18 nM[1]. It has been shown to reduce triglyceride content in white adipose tissue, skeletal muscle, and the liver of mice on a high fat diet[2]. |
| Name | 4-(5,7,7,10,10-Pentamethyl-2-nitro-7,8,9,10-tetrahydro-5H-benzo[b ]naphtho[2,3-e][1,4]diazepin-12-yl)benzoic acid |
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| Description | HX531 is a potent RXR antagonist with an IC50 of 18 nM[1]. It has been shown to reduce triglyceride content in white adipose tissue, skeletal muscle, and the liver of mice on a high fat diet[2]. |
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| Related Catalog | |
| Target |
RXR:18 nM (IC50) |
| References |
| Molecular Formula | C29H29N3O4 |
|---|---|
| Molecular Weight | 483.55800 |
| Exact Mass | 483.21600 |
| PSA | 98.72000 |
| LogP | 6.91620 |
| InChIKey | SXKPGYKPQPYJER-UHFFFAOYSA-N |
| SMILES | CN1c2ccc([N+](=O)[O-])cc2N=C(c2ccc(C(=O)O)cc2)c2cc3c(cc21)C(C)(C)CCC3(C)C |