Actinomycin X2

Modify Date: 2024-01-11 15:27:09

Actinomycin X2 structure	Common Name	Actinomycin X2
	CAS Number	18865-48-0	Molecular Weight	1269.40000
	Density	1.44g/cm3	Boiling Point	1411.4ºC at 760mmHg
	Molecular Formula	C₆₂H₈₄N₁₂O₁₇	Melting Point	N/A
	MSDS	N/A	Flash Point	807.4ºC

Use of Actinomycin X2

Actinomycin X2 (Actinomycin V), produced by many Streptomyces sp., shows strong inhibition of MRSA with a minimum inhibitory concentration (MIC) value of 0.25 μg/mL. Actinomycin X2 can be used for cancer and bacterial infection[1].

Name	actinomycin v
Synonym	More Synonyms

Description	Actinomycin X2 (Actinomycin V), produced by many Streptomyces sp., shows strong inhibition of MRSA with a minimum inhibitory concentration (MIC) value of 0.25 μg/mL. Actinomycin X2 can be used for cancer and bacterial infection[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Zhiyu Chen, et al. Anti-MRSA Activity of Actinomycin X 2 and Collismycin A Produced by Streptomyces globisporusWA5-2-37 From the Intestinal Tract of American Cockroach ( Periplaneta americana). Front Microbiol. 2020 Apr 7;11:555.

Density	1.44g/cm3
Boiling Point	1411.4ºC at 760mmHg
Molecular Formula	C₆₂H₈₄N₁₂O₁₇
Molecular Weight	1269.40000
Flash Point	807.4ºC
Exact Mass	1268.61000
PSA	377.05000
LogP	1.55260
Vapour Pressure	0mmHg at 25°C
Index of Refraction	1.661

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AU2010000

CHEMICAL NAME :: Actinomycin X2

CAS REGISTRY NUMBER :: 18865-48-0

LAST UPDATED :: 199706

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C62-H84-N12-O17

MOLECULAR WEIGHT :: 1269.58

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 300 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 38,1625,1985

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 300 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 38KLAC "Structure-Activity Relationship among the Semisynthetic Antibiotics," Perlman, D., ed., New York, Academic Press, 1977 Volume(issue)/page/year: -,427,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(2),48,1980

Hazard Codes	T+: Very toxic;
Risk Phrases	26/27/28-63
Safety Phrases	22-36/37/39-45
RIDADR	UN 2811 6.1/PG 2

5'-Deoxy(Methylthio-d3)adenosine

3h-phenoxazine,actinomycindderiv.

[A3-(4-oxo-L-proline)]-actinomycin-D

5'-S-(Methyl-d3)thioadenosine

3a-(4-oxo-l-proline)-actinomycin

5'-(Methylthio-d3)adenosine

actinomycin-V

ACTINOMYCIN X2

DC Chemicals Limited
China
Product Name: Actinomycin X2
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: ACTINOMYCIN V
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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