LXRβ agonist 17
Modify Date: 2025-11-28 19:20:44
LXRβ agonist 17 structure
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Common Name | LXRβ agonist 17 | ||
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| CAS Number | 1878259-00-7 | Molecular Weight | 488.526 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H27F3N4O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of LXRβ agonist 17A novel, potent, orally active liver X receptor β (LXRβ) agonist with Ki/EC50 of 3/21 nM, displays 27-fold selectivity over LXRα; also exhibits excellent selectivity against other nuclear hormone receptors (>3,000-fold); induces the expression of LXR target genes in vitro and in vivo. |
| Name | LXRβ agonist 17 |
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| Description | A novel, potent, orally active liver X receptor β (LXRβ) agonist with Ki/EC50 of 3/21 nM, displays 27-fold selectivity over LXRα; also exhibits excellent selectivity against other nuclear hormone receptors (>3,000-fold); induces the expression of LXR target genes in vitro and in vivo. |
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| References | References 1. Zheng Y, et al. J Med Chem. 2016 Apr 14;59(7):3264-71. View Related Products by Target Liver X Receptor (LXR) |
| Molecular Formula | C21H27F3N4O4S |
|---|---|
| Molecular Weight | 488.526 |
| InChIKey | FPVIRRAMNBCEDK-KRWDZBQOSA-N |
| SMILES | CC(C)C1CN(c2ccc(CO)c(S(C)(=O)=O)c2)CCN1c1ncc(CO)c(C(F)(F)F)n1 |