TLR7 agonist 1

Modify Date: 2025-08-25 10:22:12

TLR7 agonist 1 Structure
TLR7 agonist 1 structure
Common Name TLR7 agonist 1
CAS Number 2178156-33-5 Molecular Weight 363.46
Density N/A Boiling Point N/A
Molecular Formula C21H25N5O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TLR7 agonist 1


TLR 7 agonist 1 is a potent, selective and oral TLR7 agonist with an IC50 of 90 nM.

 Names

Name TLR 7 agonist 1

 TLR7 agonist 1 Biological Activity

Description TLR 7 agonist 1 is a potent, selective and oral TLR7 agonist with an IC50 of 90 nM.
Related Catalog
Target

TLR7:90 nM (IC50)

References

[1]. Pieters S, et al. Discovery of selective 2,4-diaminoquinazoline toll-like receptor 7 (TLR 7) agonists. Bioorg Med Chem Lett. 2018 Feb 15;28(4):711-719.

 Chemical & Physical Properties

Molecular Formula C21H25N5O
Molecular Weight 363.46
InChIKey WDFAZLUMAXOURM-AWEZNQCLSA-N
SMILES CCCCNc1nc(N)nc2cccc(C(=O)NC(C)c3ccccc3)c12
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