LSD1 inhibitor 24
Modify Date: 2025-08-24 21:04:47
LSD1 inhibitor 24 structure
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Common Name | LSD1 inhibitor 24 | ||
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| CAS Number | 1853269-07-4 | Molecular Weight | 505.982 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H25ClFN7O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of LSD1 inhibitor 24LSD1 inhibitor 24 is a novel potent, selective lysine-specific demethylase 1 (LSD1) inhibitor with IC50 of 1 nM, induces CD11b expression in THP-1 cells with EC50 of 8 nM; demonstrates attenuating the hERG inhibition and improving oral bioavailability. |
| Name | LSD1 inhibitor 24 |
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| Description | LSD1 inhibitor 24 is a novel potent, selective lysine-specific demethylase 1 (LSD1) inhibitor with IC50 of 1 nM, induces CD11b expression in THP-1 cells with EC50 of 8 nM; demonstrates attenuating the hERG inhibition and improving oral bioavailability. |
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| References | References 1. Nie Z, et al. Bioorg Med Chem Lett. 2018 Nov 3. pii: S0960-894X(18)30855-2. View Related Products by Target Histone Demethylase |
| Molecular Formula | C26H25ClFN7O |
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| Molecular Weight | 505.982 |
| InChIKey | JAKGNRQBWOOXQA-SFHVURJKSA-N |
| SMILES | CNC1CCCN(C(=O)c2nc(-c3ccc(C#N)c(F)c3)n(-c3ccc4nn(C)c(Cl)c4c3)c2C)C1 |