GSK-LSD1 2HCL

Modify Date: 2024-01-13 21:16:50

GSK-LSD1 2HCL structure	Common Name	GSK-LSD1 2HCL
	CAS Number	1431368-48-7	Molecular Weight	216.322
	Density	1.1±0.1 g/cm3	Boiling Point	347.4±42.0 °C at 760 mmHg
	Molecular Formula	C₁₄H₂₀N₂	Melting Point	N/A
	MSDS	N/A	Flash Point	206.0±19.7 °C

Use of GSK-LSD1 2HCL

GSK-LSD1 is a LSD1 inhibitor. GSK-LSD1 reduces food intake and body weight, and improves insulin sensitivity and glycemic control in mouse models of obesity. GSK-LSD1 also ameliorates NAFLD. GSK-LSD1 inhibits SARS-CoV-2-triggered cytokine release in COVID-19 PBMCs. GSK-LSD1 also inhibits cancer growth and metastasis[1][2][3].

Name	N-[(1R,2S)-2-Phenylcyclopropyl]-4-piperidinamine
Synonym	More Synonyms

Description	GSK-LSD1 is a LSD1 inhibitor. GSK-LSD1 reduces food intake and body weight, and improves insulin sensitivity and glycemic control in mouse models of obesity. GSK-LSD1 also ameliorates NAFLD. GSK-LSD1 inhibits SARS-CoV-2-triggered cytokine release in COVID-19 PBMCs. GSK-LSD1 also inhibits cancer growth and metastasis[1][2][3].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Epigenetics >> Histone Demethylase Research Areas >> Metabolic Disease
References	[1]. Ramms B, et al. Systemic LSD1 Inhibition Prevents Aberrant Remodeling of Metabolism in Obesity. Diabetes. 2022 Dec 1;71(12):2513-2529. [2]. Hong KS, et al. GSK-LSD1, an LSD1 inhibitor, quashes SARS-CoV-2-triggered cytokine release syndrome in-vitro. Signal Transduct Target Ther. 2020 Nov 17;5(1):267. [3]. Alsaqer SF, et al. Inhibition of LSD1 epigenetically attenuates oral cancer growth and metastasis. Oncotarget. 2017 Jul 27;8(43):73372-73386.

Description

Related Catalog

Research Areas >> Cancer

Research Areas >> Infection

Signaling Pathways >> Epigenetics >> Histone Demethylase

Research Areas >> Metabolic Disease

References

[1]. Ramms B, et al. Systemic LSD1 Inhibition Prevents Aberrant Remodeling of Metabolism in Obesity. Diabetes. 2022 Dec 1;71(12):2513-2529.

[2]. Hong KS, et al. GSK-LSD1, an LSD1 inhibitor, quashes SARS-CoV-2-triggered cytokine release syndrome in-vitro. Signal Transduct Target Ther. 2020 Nov 17;5(1):267.

[3]. Alsaqer SF, et al. Inhibition of LSD1 epigenetically attenuates oral cancer growth and metastasis. Oncotarget. 2017 Jul 27;8(43):73372-73386.

Density	1.1±0.1 g/cm3
Boiling Point	347.4±42.0 °C at 760 mmHg
Molecular Formula	C₁₄H₂₀N₂
Molecular Weight	216.322
Flash Point	206.0±19.7 °C
Exact Mass	216.162643
LogP	1.63
Appearance of Characters	white to beige
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.580
Storage condition	2-8°C
Water Solubility	H2O: soluble20mg/mL, clear

N-[(1R,2S)-2-Phenylcyclopropyl]-4-piperidinamine

4-Piperidinamine, N-[(1R,2S)-2-phenylcyclopropyl]-

GSK-LSD1 2HCL

GSK-LSD1 (hydrochloride)

LSD1 inhibitor

DC Chemicals Limited
China
Product Name: GSK-LSD1
Price: $400.0/100mg $800.0/250mg $1700.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: GSK-LSD1 2HCl
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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