NBI 27914 hydrochloride
Modify Date: 2025-08-21 14:31:12
NBI 27914 hydrochloride structure
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Common Name | NBI 27914 hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 184241-44-9 | Molecular Weight | 470.65100 | |
| Density | 1.417g/cm3 | Boiling Point | 483.7ºC at 760mmHg | |
| Molecular Formula | C18H21Cl5N4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 246.3ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of NBI 27914 hydrochlorideNBI-27914 is a potent and selective antagonist of CRFR1. The CRF receptors, CRFR1 and CRFR2, are members of the G protein-coupled receptor superfamily[1]. |
| Name | 5-chloro-4-N-(cyclopropylmethyl)-2-methyl-4-N-propyl-6-N-(2,4,6-trichlorophenyl)pyrimidine-4,6-diamine |
|---|---|
| Synonym | More Synonyms |
| Description | NBI-27914 is a potent and selective antagonist of CRFR1. The CRF receptors, CRFR1 and CRFR2, are members of the G protein-coupled receptor superfamily[1]. |
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| Related Catalog | |
| References |
| Density | 1.417g/cm3 |
|---|---|
| Boiling Point | 483.7ºC at 760mmHg |
| Molecular Formula | C18H21Cl5N4 |
| Molecular Weight | 470.65100 |
| Flash Point | 246.3ºC |
| Exact Mass | 468.02100 |
| PSA | 41.05000 |
| LogP | 7.64360 |
| Appearance of Characters | solid white |
| Vapour Pressure | 1.64E-09mmHg at 25°C |
| Index of Refraction | 1.649 |
| Storage condition | 2-8°C |
| Water Solubility | DMSO: 16 mg/mL at 60 °C, soluble |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| Lopac-N-3911 |
| 5-Chloro-4-(N-(cyclopropyl)methyl-N-propylamino)-2-methyl-6-(2,4,6-trichlorophenyl)aminopyridine |
| Tocris-1591 |
| NBI 27914 hydrochloride |