Acetyl-(Tyr1,D-Phe2)-GRF (1-29) amide
Modify Date: 2024-01-03 20:54:31
Acetyl-(Tyr1,D-Phe2)-GRF (1-29) amide structure
|
Common Name | Acetyl-(Tyr1,D-Phe2)-GRF (1-29) amide | ||
|---|---|---|---|---|
| CAS Number | 93965-89-0 | Molecular Weight | 3476.015 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C157H252N44O43S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Acetyl-(Tyr1,D-Phe2)-GRF (1-29) amide[Ac-Tyr1,D-Phe2]GRF 1-29, amide (human), a growth hormone releasing factor (GRF) analogue, is a vasoactive intestinal peptide (VIP) antagonist[1]. |
| Name | 1-29-Somatoliberin (human pancreatic islet), N-acetyl-2-D-phenylalanine-29-L-argininamide |
|---|---|
| Synonym | More Synonyms |
| Description | [Ac-Tyr1,D-Phe2]GRF 1-29, amide (human), a growth hormone releasing factor (GRF) analogue, is a vasoactive intestinal peptide (VIP) antagonist[1]. |
|---|---|
| Related Catalog | |
| Target |
VIP[1] |
| In Vitro | [Ac-Tyr1,D-Phe2]GRF 1-29, amide (human) 选择性抑制 VIP 和 GRF 刺激的大鼠胰腺浆膜腺苷酸环化酶活性[1]。 [Ac-Tyr1,D-Phe2]GRF 1-29, amide (human) (0.1 pM-10 nM; 3 d) 诱导 C6 细胞的剂量依赖性细胞增殖增加[2]。 Cell Proliferation Assay[2] Cell Line: C6 rat glioblastoma cells Concentration: 0.1 pM-10 nM Incubation Time: 3 days Result: Induced a dose-dependent cell proliferation increase. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C157H252N44O43S |
| Molecular Weight | 3476.015 |
| Exact Mass | 3473.860596 |
| PSA | 1475.28000 |
| LogP | -2.20 |
| Index of Refraction | 1.648 |
| N-AC-TYR(1)-PHE(2)-SOMATOTROPIN RELEASING HORMONE (1-29)-AMIDE |
| L-Argininamide, N-acetyl-L-tyrosyl-D-phenylalanyl-L-α-aspartyl-L-alanyl-L-isoleucyl-L-phenylalanyl-L-threonyl-L-asparaginyl-L-seryl-L-tyrosyl-L-arginyl-L-lysyl-L-valyl-L-leucylglycyl-L-glutaminyl- L-leucyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-leucyl-L-glutaminyl-L-α-aspartyl-L-isoleucyl-L-methionyl-L-seryl- |
| NBI 35965 hydrochloride |
| N-Acetyl-L-tyrosyl-D-phenylalanyl-L-α-aspartyl-L-alanyl-L-isoleucyl-L-phenylalanyl-L-threonyl-L-asparaginyl-L-seryl-L-tyrosyl-L-arginyl-L-lysyl-L-valyl-L-leucylglycyl-L-glutaminyl-L-leucyl-L-seryl -L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-leucyl-L-glutaminyl-L-α-aspartyl-L-isoleucyl-L-methionyl-L-seryl-L-argininamide |
| Somatoliberin (human pancreatic islet), N-acetyl-2-D-phenylalanine-29-L-argininamide-30-de-L-glutamine-31-de-L-glutamine-32-deglycine-33-de-L-glutamic acid-34-de-L-serine-35-de-L-asparagine-36-de-L-glutamine-37-de-L-glutamic acid-38-de-L-arginine-39-deglycine-40-de-L-alanine-41-de-L-arginine-42-de-L-alanine-43-de-L-arginine-44-de-L-leucinamide- |