4-Fluoro-N-(1H-indol-5-yl)benzamide

Modify Date: 2024-01-08 17:09:17

4-Fluoro-N-(1H-indol-5-yl)benzamide Structure
4-Fluoro-N-(1H-indol-5-yl)benzamide structure
Common Name 4-Fluoro-N-(1H-indol-5-yl)benzamide
CAS Number 182564-41-6 Molecular Weight 254.259
Density 1.4±0.1 g/cm3 Boiling Point 374.9±22.0 °C at 760 mmHg
Molecular Formula C15H11FN2O Melting Point N/A
MSDS N/A Flash Point 180.5±22.3 °C

 Use of 4-Fluoro-N-(1H-indol-5-yl)benzamide


Oct4 inducer-1 (compound OAC-3) is a potent Oct4 activator. Oct4 inducer-1 activates Oct4 and Nanog promoters and enhances induced pluripotent stem cells (iPSC) formation. Oct4 inducer-1 facilitates the reprogramming of cells by enhancing efficiency and shortening the reprogramming time[1].

 Names

Name oac3
Synonym More Synonyms

 4-Fluoro-N-(1H-indol-5-yl)benzamide Biological Activity

Description Oct4 inducer-1 (compound OAC-3) is a potent Oct4 activator. Oct4 inducer-1 activates Oct4 and Nanog promoters and enhances induced pluripotent stem cells (iPSC) formation. Oct4 inducer-1 facilitates the reprogramming of cells by enhancing efficiency and shortening the reprogramming time[1].
Related Catalog
In Vitro Oct4 inducer-1 (compound OAC-3; 1 μM) enhances reprogramming efficiency by activating Oct4-luc reporter and Nanog-luc reporter in embryonic stem cells (ESCs). Oct4 inducer-1 increases induced pluripotent stem cells (iPSC) generation and accelerates the appearance of iPSC-like colonies[1]. Oct4 inducer-1 (1 μM; 4F (OSKM) infected mouse embryonic fibroblast (MEF)) enhances reprogramming efficiency in iSF1 media[1].
References

[1]. Hong SY, et, al. Enhancers of induced pluripotent stem cell reprogramming. US20140154805.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 374.9±22.0 °C at 760 mmHg
Molecular Formula C15H11FN2O
Molecular Weight 254.259
Flash Point 180.5±22.3 °C
Exact Mass 254.085541
PSA 44.89000
LogP 2.77
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.721

 Synonyms

Benzamide, 4-fluoro-N-1H-indol-5-yl-
4-Fluoro-N-(1H-indol-5-yl)benzamide