182564-41-6
182564-41-6 structure
- Name: 4-Fluoro-N-(1H-indol-5-yl)benzamide
- Chemical Name: oac3
- CAS Number: 182564-41-6
- Molecular Formula: C15H11FN2O
- Molecular Weight: 254.259
- Catalog: Signaling Pathways Stem Cell/Wnt Oct3/4
- Create Date: 2016-09-21 08:06:29
- Modify Date: 2025-09-21 16:01:48
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Oct4 inducer-1 (compound OAC-3) is a potent Oct4 activator. Oct4 inducer-1 activates Oct4 and Nanog promoters and enhances induced pluripotent stem cells (iPSC) formation. Oct4 inducer-1 facilitates the reprogramming of cells by enhancing efficiency and shortening the reprogramming time[1].
| Name | oac3 |
|---|---|
| Synonyms |
Benzamide, 4-fluoro-N-1H-indol-5-yl-
4-Fluoro-N-(1H-indol-5-yl)benzamide |
| Description | Oct4 inducer-1 (compound OAC-3) is a potent Oct4 activator. Oct4 inducer-1 activates Oct4 and Nanog promoters and enhances induced pluripotent stem cells (iPSC) formation. Oct4 inducer-1 facilitates the reprogramming of cells by enhancing efficiency and shortening the reprogramming time[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Oct4 inducer-1 (compound OAC-3; 1 μM) enhances reprogramming efficiency by activating Oct4-luc reporter and Nanog-luc reporter in embryonic stem cells (ESCs). Oct4 inducer-1 increases induced pluripotent stem cells (iPSC) generation and accelerates the appearance of iPSC-like colonies[1]. Oct4 inducer-1 (1 μM; 4F (OSKM) infected mouse embryonic fibroblast (MEF)) enhances reprogramming efficiency in iSF1 media[1]. |
| References |
[1]. Hong SY, et, al. Enhancers of induced pluripotent stem cell reprogramming. US20140154805. |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 374.9±22.0 °C at 760 mmHg |
| Molecular Formula | C15H11FN2O |
| Molecular Weight | 254.259 |
| Flash Point | 180.5±22.3 °C |
| Exact Mass | 254.085541 |
| PSA | 44.89000 |
| LogP | 2.77 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.721 |