4-Fluoro-N-(1H-indol-5-yl)benzamide
Names
[ CAS No. ]:
182564-41-6
[ Name ]:
4-Fluoro-N-(1H-indol-5-yl)benzamide
[Synonym ]:
Benzamide, 4-fluoro-N-1H-indol-5-yl-
4-Fluoro-N-(1H-indol-5-yl)benzamide
Biological Activity
[Description]:
Oct4 inducer-1 (compound OAC-3) is a potent Oct4 activator. Oct4 inducer-1 activates Oct4 and Nanog promoters and enhances induced pluripotent stem cells (iPSC) formation. Oct4 inducer-1 facilitates the reprogramming of cells by enhancing efficiency and shortening the reprogramming time[1].
[Related Catalog]:
[In Vitro]
Oct4 inducer-1 (compound OAC-3; 1 μM) enhances reprogramming efficiency by activating Oct4-luc reporter and Nanog-luc reporter in embryonic stem cells (ESCs). Oct4 inducer-1 increases induced pluripotent stem cells (iPSC) generation and accelerates the appearance of iPSC-like colonies[1]. Oct4 inducer-1 (1 μM; 4F (OSKM) infected mouse embryonic fibroblast (MEF)) enhances reprogramming efficiency in iSF1 media[1].
[References]
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
374.9±22.0 °C at 760 mmHg
[ Molecular Formula ]:
C15H11FN2O
[ Molecular Weight ]:
254.259
[ Flash Point ]:
180.5±22.3 °C
[ Exact Mass ]:
254.085541
[ PSA ]:
44.89000
[ LogP ]:
2.77
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.721