KL-1333(NQO1 activator 1)

Modify Date: 2024-01-13 22:56:33

KL-1333(NQO1 activator 1) structure	Common Name	KL-1333(NQO1 activator 1)
	CAS Number	1800405-30-4	Molecular Weight	240.26
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₁₂N₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of KL-1333(NQO1 activator 1)

NQO1 activator 1 is an orally available NAD+ modulator. It reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. Elevated NAD+ levels triggers the activation of SIRT1 and AMPK, and subsequently activates PGC-1α. NQO1 activator 1 improves energy metabolism and mitochondrial dysfunction in MELAS fibroblasts[1].

Name	NQO1 activator 1

Description	NQO1 activator 1 is an orally available NAD+ modulator. It reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. Elevated NAD+ levels triggers the activation of SIRT1 and AMPK, and subsequently activates PGC-1α. NQO1 activator 1 improves energy metabolism and mitochondrial dysfunction in MELAS fibroblasts[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
Target	NQO1[1]
References	[1]. Seo KS, et al. KL1333, a Novel NAD+ Modulator, Improves Energy Metabolism and Mitochondrial Dysfunction in MELAS Fibroblasts. Front Neurol. 2018 Jul 5;9:552.

Molecular Formula	C₁₄H₁₂N₂O₂
Molecular Weight	240.26

DC Chemicals Limited
China
Product Name: KL-1333(NQO1 activator 1)
Price: $650.0/100mg $1200.0/250mg $2400.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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