NPS ALX Compound 4a dihydrochloride

Modify Date: 2025-08-26 13:19:51

NPS ALX Compound 4a dihydrochloride Structure
NPS ALX Compound 4a dihydrochloride structure
Common Name NPS ALX Compound 4a dihydrochloride
CAS Number 1781934-44-8 Molecular Weight 504.47
Density N/A Boiling Point N/A
Molecular Formula C25H27Cl2N3O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NPS ALX Compound 4a dihydrochloride


NPS ALX Compound 4a dihydrochloride is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist with an IC50 of 7.2 nM and a Ki of 0.2 nM[1].

 Names

Name NPS ALX Compound 4a dihydrochloride

 NPS ALX Compound 4a dihydrochloride Biological Activity

Description NPS ALX Compound 4a dihydrochloride is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist with an IC50 of 7.2 nM and a Ki of 0.2 nM[1].
Related Catalog
Target

5-HT6 Receptor:7.2 nM (IC50)

5-HT6 Receptor:0.2 nM (Ki)

References

[1]. Isaac M, et al. 6-Bicyclopiperazinyl-1-arylsulfonylindoles and 6-bicyclopiperidinyl-1-arylsulfonylindolesderivatives as novel, potent, and selective 5-HT6 receptor antagonists. Bioorg Med Chem Lett. 2000 Aug 7;10(15):1719-21.

 Chemical & Physical Properties

Molecular Formula C25H27Cl2N3O2S
Molecular Weight 504.47
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