FT-001
Modify Date: 2025-09-11 14:56:15
FT-001 structure
|
Common Name | FT-001 | ||
|---|---|---|---|---|
| CAS Number | 1778655-51-8 | Molecular Weight | 467.584 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H29N3O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of FT-001FT-001 is a novel potent, orally acitve inhibitor of BET bromodomain with IC50 of 0.1 uM for BRD4 BD1; inhibits the expression of MYC in the MV-4-11 cell line with IC50 of 0.46 uM, shows anti-proliferative activity with IC50 of 0.22 uM; displays complete tumor growth inhibition in mouse MV-4-11 xenograft model. |
| Name | FT-001 |
|---|
| Description | FT-001 is a novel potent, orally acitve inhibitor of BET bromodomain with IC50 of 0.1 uM for BRD4 BD1; inhibits the expression of MYC in the MV-4-11 cell line with IC50 of 0.46 uM, shows anti-proliferative activity with IC50 of 0.22 uM; displays complete tumor growth inhibition in mouse MV-4-11 xenograft model. |
|---|---|
| References | References 1. Millan DS, et al. ACS Med Chem Lett. 2017 Jul 14;8(8):847-852. View Related Products by Target Bromodomain |
| Molecular Formula | C25H29N3O4S |
|---|---|
| Molecular Weight | 467.584 |
| InChIKey | BRFIYWZYWCKGBC-KRWDZBQOSA-N |
| SMILES | CC(=O)N1c2ccc(-c3ccc(N4CCS(=O)(=O)CC4)cc3)cc2N(C(=O)C2CC2)CC1C |