FT-001

Names

[ Name ]:
FT-001

Biological Activity

[Description]:

FT-001 is a novel potent, orally acitve inhibitor of BET bromodomain with IC50 of 0.1 uM for BRD4 BD1; inhibits the expression of MYC in the MV-4-11 cell line with IC50 of 0.46 uM, shows anti-proliferative activity with IC50 of 0.22 uM; displays complete tumor growth inhibition in mouse MV-4-11 xenograft model.

[References]

References 1. Millan DS, et al. ACS Med Chem Lett. 2017 Jul 14;8(8):847-852. View Related Products by Target Bromodomain

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₂₉N₃O₄S

[ Molecular Weight ]:
467.584

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.